diff --git a/commands/event.go b/commands/event.go
index 96d5e921..65ddd3da 100644
--- a/commands/event.go
+++ b/commands/event.go
@@ -40,6 +40,8 @@ type Event[MetaType any] struct {
 	Proc    *Processor[MetaType]
 	Handler *Handler[MetaType]
 	Meta    MetaType
+
+	redactedBy id.EventID
 }
 
 var IDHTMLParser = &format.HTMLParser{
@@ -71,7 +73,14 @@ func ParseEvent[MetaType any](ctx context.Context, evt *event.Event) *Event[Meta
 	if len(text) == 0 {
 		return nil
 	}
+	return RawTextToEvent[MetaType](ctx, evt, text)
+}
+
+func RawTextToEvent[MetaType any](ctx context.Context, evt *event.Event, text string) *Event[MetaType] {
 	parts := strings.Fields(text)
+	if len(parts) == 0 {
+		parts = []string{""}
+	}
 	return &Event[MetaType]{
 		Event:    evt,
 		RawInput: text,
@@ -91,6 +100,7 @@ type ReplyOpts struct {
 	SendAsText       bool
 	Edit             id.EventID
 	OverrideMentions *event.Mentions
+	Extra            map[string]any
 }
 
 func (evt *Event[MetaType]) Reply(msg string, args ...any) id.EventID {
@@ -117,7 +127,14 @@ func (evt *Event[MetaType]) Respond(msg string, opts ReplyOpts) id.EventID {
 	if opts.OverrideMentions != nil {
 		content.Mentions = opts.OverrideMentions
 	}
-	resp, err := evt.Proc.Client.SendMessageEvent(evt.Ctx, evt.RoomID, event.EventMessage, content)
+	var wrapped any = &content
+	if opts.Extra != nil {
+		wrapped = &event.Content{
+			Parsed: &content,
+			Raw:    opts.Extra,
+		}
+	}
+	resp, err := evt.Proc.Client.SendMessageEvent(evt.Ctx, evt.RoomID, event.EventMessage, wrapped)
 	if err != nil {
 		zerolog.Ctx(evt.Ctx).Err(err).Msg("Failed to send reply")
 		return ""
@@ -135,11 +152,15 @@ func (evt *Event[MetaType]) React(emoji string) id.EventID {
 }
 
 func (evt *Event[MetaType]) Redact() id.EventID {
+	if evt.redactedBy != "" {
+		return evt.redactedBy
+	}
 	resp, err := evt.Proc.Client.RedactEvent(evt.Ctx, evt.RoomID, evt.ID)
 	if err != nil {
 		zerolog.Ctx(evt.Ctx).Err(err).Msg("Failed to redact command")
 		return ""
 	}
+	evt.redactedBy = resp.EventID
 	return resp.EventID
 }
 
diff --git a/commands/processor.go b/commands/processor.go
index c4940526..9341329b 100644
--- a/commands/processor.go
+++ b/commands/processor.go
@@ -26,6 +26,8 @@ type Processor[MetaType any] struct {
 	LogArgs      bool
 	PreValidator PreValidator[MetaType]
 	Meta         MetaType
+
+	ReactionCommandPrefix string
 }
 
 // UnknownCommandName is the name of the fallback handler which is used if no other handler is found.
@@ -65,7 +67,13 @@ func (proc *Processor[MetaType]) Process(ctx context.Context, evt *event.Event)
 			}
 		}
 	}()
-	parsed := ParseEvent[MetaType](ctx, evt)
+	var parsed *Event[MetaType]
+	switch evt.Type {
+	case event.EventReaction:
+		parsed = proc.ParseReaction(ctx, evt)
+	case event.EventMessage:
+		parsed = ParseEvent[MetaType](ctx, evt)
+	}
 	if parsed == nil || !proc.PreValidator.Validate(parsed) {
 		return
 	}
diff --git a/commands/reactions.go b/commands/reactions.go
new file mode 100644
index 00000000..0df372e5
--- /dev/null
+++ b/commands/reactions.go
@@ -0,0 +1,125 @@
+// Copyright (c) 2025 Tulir Asokan
+//
+// This Source Code Form is subject to the terms of the Mozilla Public
+// License, v. 2.0. If a copy of the MPL was not distributed with this
+// file, You can obtain one at http://mozilla.org/MPL/2.0/.
+
+package commands
+
+import (
+	"context"
+	"strings"
+
+	"github.com/rs/zerolog"
+
+	"maunium.net/go/mautrix"
+	"maunium.net/go/mautrix/event"
+)
+
+const ReactionCommandsKey = "fi.mau.reaction_commands"
+const ReactionMultiUseKey = "fi.mau.reaction_multi_use"
+
+func (proc *Processor[MetaType]) ParseReaction(ctx context.Context, evt *event.Event) *Event[MetaType] {
+	content, ok := evt.Content.Parsed.(*event.ReactionEventContent)
+	if !ok {
+		return nil
+	}
+	evtID := content.RelatesTo.EventID
+	if evtID == "" || !strings.HasPrefix(content.RelatesTo.Key, proc.ReactionCommandPrefix) {
+		return nil
+	}
+	targetEvt, err := proc.Client.GetEvent(ctx, evt.RoomID, evtID)
+	if err != nil {
+		zerolog.Ctx(ctx).Err(err).Stringer("target_event_id", evtID).Msg("Failed to get target event for reaction")
+		return nil
+	} else if targetEvt.Sender != proc.Client.UserID || targetEvt.Unsigned.RedactedBecause != nil {
+		return nil
+	}
+	if targetEvt.Type == event.EventEncrypted {
+		if proc.Client.Crypto == nil {
+			zerolog.Ctx(ctx).Warn().
+				Stringer("target_event_id", evtID).
+				Msg("Received reaction to encrypted event, but don't have crypto helper in client")
+			return nil
+		}
+		_ = targetEvt.Content.ParseRaw(targetEvt.Type)
+		targetEvt, err = proc.Client.Crypto.Decrypt(ctx, targetEvt)
+		if err != nil {
+			zerolog.Ctx(ctx).Err(err).
+				Stringer("target_event_id", evtID).
+				Msg("Failed to decrypt target event for reaction")
+			return nil
+		}
+	}
+	reactionCommands, ok := targetEvt.Content.Raw[ReactionCommandsKey].(map[string]any)
+	if !ok {
+		zerolog.Ctx(ctx).Trace().
+			Stringer("target_event_id", evtID).
+			Msg("Reaction target event doesn't have commands key")
+		return nil
+	}
+	isMultiUse, _ := targetEvt.Content.Raw[ReactionMultiUseKey].(bool)
+	rawCmd, ok := reactionCommands[content.RelatesTo.Key]
+	if !ok {
+		zerolog.Ctx(ctx).Debug().
+			Stringer("target_event_id", evtID).
+			Str("reaction_key", content.RelatesTo.Key).
+			Msg("Reaction command not found in target event")
+		return nil
+	}
+	cmdString, ok := rawCmd.(string)
+	if !ok {
+		zerolog.Ctx(ctx).Debug().
+			Stringer("target_event_id", evtID).
+			Str("reaction_key", content.RelatesTo.Key).
+			Msg("Reaction command data is invalid")
+		return nil
+	}
+	wrappedEvt := RawTextToEvent[MetaType](ctx, evt, cmdString)
+	wrappedEvt.Proc = proc
+	wrappedEvt.Redact()
+	if !isMultiUse {
+		DeleteAllReactions(ctx, proc.Client, evt)
+	}
+	if cmdString == "" {
+		return nil
+	}
+	return wrappedEvt
+}
+
+func DeleteAllReactionsCommandFunc[MetaType any](ce *Event[MetaType]) {
+	DeleteAllReactions(ce.Ctx, ce.Proc.Client, ce.Event)
+}
+
+func DeleteAllReactions(ctx context.Context, client *mautrix.Client, evt *event.Event) {
+	rel, ok := evt.Content.Parsed.(event.Relatable)
+	if !ok {
+		return
+	}
+	relation := rel.OptionalGetRelatesTo()
+	if relation == nil {
+		return
+	}
+	targetEvt := relation.GetReplyTo()
+	if targetEvt == "" {
+		targetEvt = relation.GetAnnotationID()
+	}
+	if targetEvt == "" {
+		return
+	}
+	relations, err := client.GetRelations(ctx, evt.RoomID, targetEvt, &mautrix.ReqGetRelations{
+		RelationType: event.RelAnnotation,
+		EventType:    event.EventReaction,
+		Limit:        20,
+	})
+	if err != nil {
+		zerolog.Ctx(ctx).Err(err).Msg("Failed to get reactions to delete")
+		return
+	}
+	for _, relEvt := range relations.Chunk {
+		_, err = client.RedactEvent(ctx, relEvt.RoomID, relEvt.ID)
+		if err != nil {
+			zerolog.Ctx(ctx).Err(err).Stringer("event_id", relEvt.ID).Msg("Failed to redact reaction event")
+		}
+	}
+}