#' Clinical Trial for Sepsis desease #' #' Simulated clinical trial with two groups treatment about sepsis desease. See #' details. #' #' This dataset is taken from #' \href{http://biopharmnet.com/subgroup-analysis-software/}{SIDES #' method}. #' #' \code{Sepsis} contains simulated data on 470 subjects with a binary outcome #' survival, that stores survival status for patient after 28 days of treatment, #' value of 1 for subjects who died after 28 days and 0 otherwise. There are 11 #' covariates, listed below, all of which are numerical variables. #' #' Note that contrary to the original dataset used in SIDES, missing values have #' been imputed by random forest \code{(randomForest::rfImpute())}. See file #' data-raw/sepsis.R for more details. #' #' True subgroup is \emph{PRAPACHE <= 26 & AGE <= 49.80}. \emph{NOTE:} This #' subgroup is defined with the \emph{lower} event rate (survival = 1) in #' treatement arm. #' #' @format 470 patients and 13 variables. \describe{ \item{survival}{binary #' outcome} \item{THERAPY}{1 for active treatment, 0 for control treatment} #' \item{TIMFIRST}{Time from first sepsis-organ fail to start drug} #' \item{AGE}{Patient age in years} \item{BLLPLAT}{Baseline local platelets} #' \item{blSOFA}{Sum of baselin sofa (cardiovascular, hematology, #' hepaticrenal, and respiration scores)} \item{BLLCREAT}{Base creatinine} #' \item{ORGANNUM}{Number of baseline organ failures} #' \item{PRAPACHE}{Pre-infusion apache-ii score} \item{BLGCS}{Base GLASGOW #' coma scale score} \item{BLIL6}{Baseline serum IL-6 concentration} #' \item{BLADL}{Baseline activity of daily living score} #' \item{BLLBILI}{Baseline local bilirubin} } #' #' @usage data(sepsis) #' @docType data #' @source #' \url{http://biopharmnet.com/subgroup-analysis-software/} #' #' @name sepsis NULL