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46 lines
1.8 KiB
R
46 lines
1.8 KiB
R
% Generated by roxygen2: do not edit by hand
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% Please edit documentation in R/data.R
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\docType{data}
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\name{sepsis}
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\alias{sepsis}
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\title{Clinical Trial for Sepsis desease}
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\format{470 patients and 13 variables. \describe{ \item{survival}{binary
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outcome} \item{THERAPY}{1 for active treatment, 0 for control treatment}
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\item{TIMFIRST}{Time from first sepsis-organ fail to start drug}
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\item{AGE}{Patient age in years} \item{BLLPLAT}{Baseline local platelets}
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\item{blSOFA}{Sum of baselin sofa (cardiovascular, hematology,
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hepaticrenal, and respiration scores)} \item{BLLCREAT}{Base creatinine}
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\item{ORGANNUM}{Number of baseline organ failures}
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\item{PRAPACHE}{Pre-infusion apache-ii score} \item{BLGCS}{Base GLASGOW
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coma scale score} \item{BLIL6}{Baseline serum IL-6 concentration}
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\item{BLADL}{Baseline activity of daily living score}
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\item{BLLBILI}{Baseline local bilirubin} }}
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\source{
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\url{http://biopharmnet.com/subgroup-analysis-software/}
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}
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\usage{
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data(sepsis)
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}
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\description{
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Simulated clinical trial with two groups treatment about sepsis desease. See
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details.
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}
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\details{
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This dataset is taken from
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\href{http://biopharmnet.com/subgroup-analysis-software/}{SIDES
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method}.
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\code{Sepsis} contains simulated data on 470 subjects with a binary outcome
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survival, that stores survival status for patient after 28 days of treatment,
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value of 1 for subjects who died after 28 days and 0 otherwise. There are 11
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covariates, listed below, all of which are numerical variables.
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Note that contrary to the original dataset used in SIDES, missing values have
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been imputed by random forest \code{(randomForest::rfImpute())}. See file
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data-raw/sepsis.R for more details.
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True subgroup is \emph{PRAPACHE <= 26 & AGE <= 49.80}. \emph{NOTE:} This
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subgroup is defined with the \emph{lower} event rate (survival = 1) in
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treatement arm.
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}
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