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41 lines
1.7 KiB
R
41 lines
1.7 KiB
R
#' Clinical Trial for Sepsis desease
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#'
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#' Simulated clinical trial with two groups treatment about sepsis desease. See details.
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#'
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#' This dataset is taken from
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#' \href{http://biopharmnet.com/wiki/Software_for_subgroup_identification_and_analysis}{SIDES
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#' method}.
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#'
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#' \code{Sepsis} contains simulated data on 470 subjects with a binary outcome
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#' survival, that stores survival status for patient after 28 days of treatment,
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#' value of 1 for subjects who died after 28 days and 0 otherwise. There are 11
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#' covariates, listed below, all of which are numerical variables.
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#'
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#' Note that contrary to the original dataset used in SIDES, missing values have
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#' been imputed by random forest \code{(randomForest::rfImpute())}
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#'
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#' True subgroup is \emph{PRAPACHE <= 26 & AGE <= 49.80}
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#'
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#' @format 470 patients and 13 variables.
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#' \describe{
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#' \item{survival}{binary outcome}
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#' \item{THERAPY}{1 for active treatment, 0 for control treatment}
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#' \item{TIMFIRST}{Time from first sepsis-organ fail to start drug}
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#' \item{AGE}{Patient age in years}
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#' \item{BLLPLAT}{Baseline local platelets}
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#' \item{blSOFA}{Sum of baselin sofa (cardiovascular, hematology, hepaticrenal, and respiration scores)}
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#' \item{BLLCREAT}{Base creatinine}
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#' \item{ORGANNUM}{Number of baseline organ failures}
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#' \item{PRAPACHE}{Pre-infusion apache-ii score}
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#' \item{BLGCS}{Base GLASGOW coma scale score}
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#' \item{BLIL6}{Baseline serum IL-6 concentration}
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#' \item{BLADL}{Baseline activity of daily living score}
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#' \item{BLLBILI}{Baseline local bilirubin}
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#' }
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#'
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#' @usage data(sepsis)
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#' @docType data
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#' @source \url{http://biopharmnet.com/wiki/Software_for_subgroup_identification_and_analysis}
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#' @name sepsis
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NULL
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